The desire for performance enhancement and muscle building has been a longstanding aspiration for men throughout history. The pursuit of physical strength, endurance, and an impressive physique has been a cultural and societal norm in various contexts. Testolone-RAD140 is a selective androgen receptor modulator (SARM) that has gained significant attention in the world of performance enhancement and muscle building along with treating testosterone deficiency.


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Developed by Radius Health Inc., RAD-140 is part of a new generation of compounds designed to target androgen receptors selectively, offering the potential benefits of traditional anabolic steroids without many of the associated side effects. {R}

Selective androgen receptor modulators (SARMs) are a class of compounds that selectively bind to androgen receptors in the body. Unlike traditional anabolic steroids, which often affect various tissues and organs, SARMs are designed to target specific receptors in muscle and bone cells. This selectivity is believed to reduce the risk of adverse effects on other organs, making SARMs an attractive option for those seeking performance enhancement with potentially fewer side effects. For a complete guide to SARMs click here for an Introduction to SARMs.

Product Information

RAD-140 is typically available in the form of capsules, liquid solutions, or powders. The form may vary between different manufacturers or suppliers.

RAD-140 is known for its high affinity for androgen receptors in the body, particularly those in muscle and bone tissues. When RAD-140 binds to these receptors, it triggers a series of events that promote anabolic effects, such as increased protein synthesis and muscle growth. Additionally, RAD-140 is thought to have a relatively low impact on androgen receptors in the prostate, potentially reducing the risk of prostate-related issues seen with some traditional androgenic compounds. {R}

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Popularity in the Bodybuilding Industry:

One of the primary reasons individuals turn to RAD-140 is its potential to enhance muscle growth and physical performance. Studies have shown promising results, with RAD-140 demonstrating an ability to increase lean muscle mass without the undesirable side effects associated with traditional steroids. Athletes and bodybuilders are particularly interested in RAD-140 due to its potential to offer similar benefits to testosterone without the risk of estrogenic side effects, such as water retention and gynecomastia.

Mechanism of Action

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The mechanism of action of Testolone (RAD-140) involves its selective binding to androgen receptors in the body. As a selective androgen receptor modulator (SARM), RAD-140 is designed to interact specifically with androgen receptors, which are proteins found in cells that respond to androgens, such as testosterone. Unlike traditional anabolic steroids, RAD-140 is intended to have a more targeted effect on muscle and bone tissues while minimizing impact on other organs. {R} The mechanism of action involves:

Androgen Receptor Binding: RAD-140 selectively binds to androgen receptors, particularly those in muscle and bone tissues. This selectivity is a key characteristic of SARMs and is intended to reduce the risk of undesirable side effects on other organs, such as the prostate. {R}

Anabolic Effects on Muscle Tissue: Once bound to androgen receptors in muscle cells, RAD-140 stimulates anabolic effects. This includes an increase in protein synthesis, which is the process by which cells build proteins from amino acids. Elevated protein synthesis contributes to muscle growth and repair. {R}

Increased Muscle Mass/ Physical Performance: The primary goal of RAD-140 is to promote the growth of lean muscle mass. This is particularly beneficial for individuals involved in resistance training or bodybuilding, as it can enhance the effects of exercise on muscle development. RAD-140’s impact on androgen receptors in muscle tissues may result in improved physical performance. Users often report increased strength, endurance, and stamina, making it appealing to athletes and fitness enthusiasts. {R}

Benefits – Testolone-RAD140

Testolone, commonly known as RAD-140, is a selective androgen receptor modulator (SARM) that has garnered attention for its potential benefits in the realm of muscle building, physical performance, and overall well-being. While research is still ongoing, potential advantages associated with RAD-140 include:

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1. Muscle Growth and Lean Mass:

RAD-140 is renowned for its anabolic properties, promoting an increase in lean muscle mass. This makes it a popular choice among bodybuilders and athletes looking to enhance their physique along with countering muscle wasting. {R}

2. Improved Physical Performance:

Users of RAD-140 often report enhanced athletic performance, including increased endurance, strength, and stamina. This performance improvement can be attributed to the compound’s impact on muscle development and its ability to optimize the efficiency of energy utilization during physical activities. {R}

3. Fat Loss:

Some studies suggest that RAD-140 may contribute to fat loss, particularly when combined with a proper diet and exercise regimen. The increased lean muscle mass can potentially boost metabolism, aiding in the reduction of body fat. {R}

4. Breast Cancer Treatment:

RAD-140 is being investigated as a potential treatment for breast cancer in postmenopausal women, with a focus on Androgen and Estrogen Receptor-positive (AR/ER+) type, which is known to be sensitive to hormone-based medications, such as SARM RAD 140. This drug has shown promising results in fighting cancer by affecting these receptors. {R}

5. Potential Bone Health Benefits:

Androgen receptors play a crucial role in maintaining bone density and strength. RAD-140’s affinity for these receptors has led to investigations into its potential for improving bone health, making it a subject of interest in the treatment of conditions such as osteoporosis. {R}

6. Minimal Estrogenic Side Effects:

Unlike traditional anabolic steroids, RAD-140 is designed to be selective in its binding to androgen receptors, which may reduce the risk of estrogenic side effects such as water retention and gynecomastia. This can be particularly advantageous for individuals sensitive to these side effects. {R}

7. Neuroprotective Effects:

Some research suggests that RAD-140 may have neuroprotective properties, potentially benefiting the nervous system. While more studies are needed to fully understand these effects, the neuroprotective potential adds another layer to the compound’s overall appeal. {R}

8. Rapid Action:

Users often report that RAD-140 has a relatively quick onset of action, with noticeable effects in terms of muscle growth and increased energy levels. This rapid response can be appealing to those seeking more immediate results. {R}

Side Effects

While Testolone (RAD-140) has shown promise in preclinical characterization studies and user experiences for its potential benefits when consumed at normal levels, however, some reported side effects associated with RAD-140 use include headaches, nausea, insomnia, increased aggression, and, in some cases, liver injury.

Healthcare professionals are advised to be consulted before use, as some research indicates the risk of liver damage and heart attack with the use of the compound. Moreover, SARMs in general are often linked to causing acute myocarditis in individuals.

Is RAD-140 Legal?

RAD-140 can be purchased legally as a research compound, but it is prohibited for use by athletes and professionals as of yet according to the World Anti-Doping Agency.


For beginners, a recommended starting dosage of 10mg per day which can be enhanced up to 20 mg per day with a cycle length of 8-10 weeks. 

Half-Life of RAD-140?

The half-life of RAD-140 is generally considered at 16 hours, however, some researchers believe that the compound has a long half-life of up to 60 hours.

RAD-140 vs. RAD-150

RAD 140, known as Testolone, and RAD 150 are two distinct selective androgen receptor modulators (SARMs) designed for research purposes. While both target muscle and bone tissues, RAD 140 primarily focuses on muscle and bone, binding selectively to androgen receptors to influence gene expression related to muscle growth and bone health. It is recognized for promoting lean muscle mass, strength gains, and potential fat loss, with research applications exploring its efficacy in treating muscle wasting diseases and osteoporosis.

On the other hand, RAD 150 exhibits a high affinity for androgen receptors in muscle tissues, sharing similarities with RAD 140. Research suggests RAD 150 may offer enhanced anabolic effects, contributing to muscle growth. However, direct comparison studies between RAD 140 and RAD 150 are limited. It’s essential to note that both compounds lack extensive human clinical data.

Where to Buy RAD-140 Online:

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The best sites for buying Testolone RAD 140 and other nutritional supplements and medications online are Pure Rawz and RCD.Bio and Behemoth Labz. To be the best suppliers of research chemicals, all the 3 online stores provide reference materials with every product they sell.


Testolone (RAD-140) represents a promising development in the world of SARMs, offering potential benefits for muscle building, performance enhancement, and bone health. As the scientific community continues to explore the applications and safety of RAD-140, it will be interesting to see how this selective androgen receptor modulator evolves in the realm of sports performance and muscle development.


About Author

Calvin Ramos

Calvin Ramos is a dedicated research and fitness enthusiast with a passion for helping individuals achieve their health and wellness goals. With years of experience in the fitness industry and a deep commitment to staying up-to-date with the latest research and developments in the field, Calvin brings a wealth of knowledge and expertise to his articles. As a fitness coach and nutrition specialist, Calvin has helped countless clients transform their lives through personalized training programs and evidence-based dietary recommendations. He holds a Bachelor's degree in Exercise Science and Nutrition from University and is certified in personal training and sports nutrition. Calvin's writing reflects his commitment to providing accurate and trustworthy information to empower readers on their fitness journeys. He believes in the power of education and strives to make complex fitness concepts accessible to everyone. His articles are thoroughly researched, drawing on the latest scientific studies and expert insights. When he's not writing or coaching, you can find Calvin in the gym, experimenting with new workout routines, or exploring the latest advancements in fitness technology. His dedication to the field of fitness and wellness is evident in his articles, which aim to inspire and inform readers on their path to a healthier, happier life.