MK-677 IBUTAMOREN Overview Nutrobal (MK-677) is an orally administrated growth hormone secretagogue originally developed by Reverse Pharmacology. A secretagogue is the term for a substance that chemically signals for the pituitary gland to secrete growth hormone. In other words, Nutrobal could be compared to peptides like GHRP-6 or Ipamorelin, only it doesn’t require any injections […]
BAC vs Sterile Water This article will briefly discuss the differences between BAC-water and Sterile water for the reconstitution of peptides. If you haven’t yet, read our short article on Lyophilized Peptides and their reconstitution in liquid suspensions – click here. BAC-water contains a small percentage of benzo alcohol which makes it better at reconstituting […]
CARDARINE GW-501516 Overview GW-501516 (GW1516 or GSK-516) is a drug that acts as a PPARδ modulator. GW-501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue, and GW 501516 has been demonstrated to reverse metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation. It has […]
Side Effects of SARMs General side effects are few, unless taken in high doses for a long period. Running it for 4 weeks or more may produce these side effects. Testicular atrophy (a reduction in size of male reproductive organs) Gynecomastia Virilization in women (development of male characteristics) Baldness Acne Controlling SARMS usage will help […]
GW-0742 Overview GW-0742 shows activity against hPPARα, hPPARγ and hPPARδ with EC50 of 1.1 μM, 2 μM and 1 nM, respectively, in cell based transactivation assay. GW-0742 (0.2 μM and 1 μM) significant increases in reporter activity of PPARβ/δ in N/TERT-1 keratinocytes. GW0742 (1 μM) results in significant inhibition in the average number of N/TERT-1 […]
Lyophilized Peptides Peptides come in a lyophilized form. This process of lyophilization, also known as freeze-drying, is a process that results in preserving biological material, by removing water from the specific material. In order to achieve this, the sample needs to be frozen and dried under a vacuum, at extremely low temperatures. Lyophilized peptides have […]
Subcutaneous injections: Subcutaneous (sub-q) injections involve injecting a medication into the fatty tissue between the skin and muscle on various parts of the body. Sub-q injections are generally absorbed slower, over a period of 24 hours or more. Use Insulin- or short (1.5-1 inch) needles to inject sub-q. Subcutaneous Injection spots: There are many places […]
STENABOLIC SR-9009 Overview Stenabolic (SR9009) is a PPAR alpha modifier drug that is still in development as of 2015. Its creator is professor Thomas Burris of the Scripps research institute. Interestingly, it is sold as a SARM and research chemical, and it can be compared to Cardarine (GW-501516), as it is also an agonist of […]
YK-11 Overview YK11 is one of the newer SARMs on the market, offering a powerful alternative to anabolic steroids. The drug is one of the latest discoveries in the SARMs group, only properly identified in 2011 by Yuichiro Kanno. After going on to publish the results of his research, YK11 was identified as having the […]
SR-9011 Overview SR9011 is a REV-ERB-α/β agonist. REV-ERB nuclear receptors have a critical role in feedback regulation of the circadian oscillator. Both Bmal1 and Clock are direct REV-ERB target genes and loss of REV-ERB-α alters circadian behaviour. In vitro: SR9011 dose-dependently increased the REV-ERB-dependent repressor activity assessed in HEK293 cells. In addition, SR9011 potently and […]
