Have you always heard about all the amazing benefits of SARMS and are ready to get your hands on one of the best ones but afraid of any side effects that might come with them? Don’t worry! We have got you all covered because in this article we will discuss the one product (Cardarine) which is extremely beneficial as compared to any SARM in the market but when it comes to side effects it isn’t essentially a SARM at all. Have I got your attention yet? Let’s look deeper into the product that is not a selective androgen receptor modulator but still has it all. Rather than affecting androgen receptors, Cardarine works on the PPAR pathway as a PPAR Receptor Agonist. Hence, Cardarine is not hormonal, not anabolic, and does not require post-cycle therapy (PCT).

Product Information

GW501516 was initially discovered during a research collaboration between GSK and Ligand Pharmaceuticals that began in 1992. GW501516, also known as Cardarine, is a PPARδ receptor agonist which was initially developed for metabolic and cardiovascular diseases.

As discussed above, cardarine is a PPAR (Peroxisome proliferator-activated receptor) agonist. Unlike SARMs, which have this tendency of selectively binding to ARs (androgen receptors), cardarine is very selective in its targeting of PPAR receptors. The human body typically has 47 nuclear receptors. While other compounds in the market are generic in their targeting of tissues and body receptors, cardarine is perfect for people looking for faster muscles’ gain, fat loss and endurance.

Peroxisome Proliferator-Activated Receptor Modulator

Thus it is a PPAR modulator that doesn’t affect the other remaining nuclear receptors including steroid receptors, resulting in minimising unwanted side effects.

Due to its selective nature, this selective receptor modulator not only causes zero potential androgenic side effects to other parts of the body (such as muscle loss) but also helps reduce levels of high-density lipoproteins and bad cholesterol.

How does Cardarine (GW-501516) Work?

The PPAR receptors are located at various points in the body, one of which is muscles. Cardarine binds with PPAR and triggers multiple effects including reduction in glucose metabolism, fat loss, and enhancing endurance.

Cardarine exaggerates the rate at which the body consumes stored body fat resultantly converting it into energy.

Popularity in the Bodybuilding industry

With further research, the drug has gained its popularity in the bodybuilding industry for its potential role in muscle growth, increased muscle mass, and gaining lean muscle. 

As a partial agonist, cardarine is admired among bodybuilders for its ability to stimulate significant strength gains and improvements in muscle mass. The best thing is that you can expect dramatic results within a short period of time by adding this into your diet besides your training regime. This is one product that you should buy if endurance, muscle mass, and strength gains are what you’re seeking.

Bodybuilders absolutely love cardarine as it fits very well into a cutting stack. Moreover, it has been found to lower harmful LDL cholesterol and boost healthy HDL cholesterol.

Cardarine Benefits

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Cardarine belongs to the class of chemicals known as PPAR agonists (peroxisome proliferator-activated receptor agonists). It was initially developed for its potential therapeutic benefits, particularly in the treatment of metabolic and cardiovascular conditions. However, it has gained attention in the fitness and bodybuilding communities for its potential performance-enhancing and fat-burning properties.

Here are some potential benefits that have been associated with Cardarine, based on preclinical and anecdotal evidence:

  1. Increased Endurance: Cardarine has been reported to enhance endurance and stamina and give lean muscle mass. It can improve the body’s ability to utilize oxygen, which may benefit athletes and individuals involved in cardiovascular activities.{R}
  2. Fat Loss: Some users claim that Cardarine can promote fat loss by increasing the body’s metabolism. It is believed to enhance the utilization of stored fat for energy and additionally treat metabolic disorders.{R}
  3. Improved Cardiovascular Health: Cardarine has been studied for its potential benefits in reducing the risk of cardiovascular diseases. It may help lower bad cholesterol (LDL) and improve lipid profiles..{R}
  4. Anti-Inflammatory Properties: Some research suggests that Cardarine may have anti-inflammatory effects, which could be beneficial for overall health and potentially reduce muscle soreness and recovery time.{R}
  5. Enhanced Muscle Preservation: There are claims that Cardarine can help preserve muscle mass and help in muscle building during periods of calorie deficit or intense exercise, which can be particularly useful for bodybuilders and athletes looking to cut weight..{R}
  6. Potential Anti-Cancer Properties: Some studies in animals have shown that Cardarine may inhibit the growth of certain types of cancer cells. However, this area of research is still in its early stages.{R}

To summarize, the drug can potentially help people avoid heart attacks, cardiovascular diseases, strokes, blocked arteries, and much more. It’s not often that performance-enhancing drugs do wonders in promoting health like cardiovascular health and well-being, but that is Cardarine for you. It really is a lifesaver.

Cardarine CrossFit

Cardarine is THE product that athletes look for when it comes to HIIT training, which is a focal part of CrossFit. It enhances your endurance like no other compound as it unleashes limitless energy by raising testosterone levels. The compound is not androgenic, thus giving it the added advantage of not having any requirement of post-cycle therapy.

This compound does a bit more than just boost endurance. GW-501516 stimulates glucose uptake in skeletal muscle tissue, and reverses metabolic abnormalities in obese men with pre-diabetic metabolic syndrome, most likely by stimulating fatty acid oxidation.

Does Cardarine give you energy?

Cardarine (GW-501516) is often associated with an increase in endurance and stamina, which may result in a perception of having more energy. However, it’s important to understand that Cardarine doesn’t provide energy in the way that stimulants like caffeine do. Instead, it can enhance the body’s ability to utilize oxygen and improve aerobic capacity, leading to improved endurance during physical activities.

The increased endurance and stamina associated with Cardarine use may make it feel like you have more energy, especially during cardio-intensive workouts or other forms of aerobic exercise. Users have reported improved performance and the ability to exercise for longer durations without getting fatigued quickly

Is Cardarine Legal?

Though not FDA-approved yet, cardarine has given a completely new dimension to the popularity of supplements and may end up gaining not even unmatched popularity but resolving legality issues as well.

The reason behind this is the fact that besides being proven to be a game changer for the fitness industry with tremendous benefits of muscle gain and fat loss, the compound is less prone to side effects making it a healthier option instead.

As a result, the drug has become an innovation in the industry of the supplements due to its novel class and fewer side effects. We hope that in days to come FDA might have a considerate stance towards the potentially beneficial supplement. However, till that time always consult a healthcare provider before the use of cardarine. If you are an athlete, you can get into trouble if tested positive with cardarine by the world Anti-Doping Agency.

Side Effects of Cardarine

It’s important to note that while Cardarine has produced some outstanding results during drug tests in animal studies and anecdotal reports, it has not been approved for human consumption by regulatory agencies like the FDA. There are, however, some potential risks including hormonal imbalances, and other potential side effects. Moreover, Cardarine is banned by sports organizations such as World Anti-Doping Agency’s as it is still a research chemical.

If you are considering using Cardarine or any similar compounds, it’s crucial to consult with a healthcare professional who can provide guidance, monitor your health, and ensure that it is safe and appropriate for your individual circumstances.

Dosage- Cardarine

An optimum effective limit, especilaly when starting, should be 10 mg per day. It is suggested to start as low as possible for the first cycle but be consistent in use daily for best results.

Half-Life of Cardarine

The half-life ranges from 12-24 hours, so if you do increase the dosage to 20mg, it is suggested to take it twice a day at 10 mg in the morning and at night each.

Cardarine cycle length

Cardarine must be taken for a straight 6 weeks on a daily basis.

Cardarine dosage for women

Cardarine is equally safe for men and women alike as it doesn’t pose any risk of androgenic side effects. 10mg daily for women is suggested dosage for the duration of 6 weeks.

Cardarine Research

In a research study conducted on mice, GW501516 increased the running distance of mice on endurance tolerance tests.

In order to test this, we treated age-matched wild-type KM cohorts with either vehicle or GW501516 for 3 weeks. Trained mice increased their exhaustive running distance by 744.4 m (31.2%) after 3 weeks of GW501516 treatment. GW501516 treatment for 3 weeks in sedentary KM mice also significantly enhanced running distance by 750.3 m (68.6%) compared to untrained control mice. Similarly, even GW501516 treatment alone (NG group) for only 1 week improved the running distance by 671.8 m (48.6%) compared to the vehicle control group.{R}

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About Author

Calvin Ramos

Calvin Ramos is a dedicated research and fitness enthusiast with a passion for helping individuals achieve their health and wellness goals. With years of experience in the fitness industry and a deep commitment to staying up-to-date with the latest research and developments in the field, Calvin brings a wealth of knowledge and expertise to his articles. As a fitness coach and nutrition specialist, Calvin has helped countless clients transform their lives through personalized training programs and evidence-based dietary recommendations. He holds a Bachelor's degree in Exercise Science and Nutrition from University and is certified in personal training and sports nutrition. Calvin's writing reflects his commitment to providing accurate and trustworthy information to empower readers on their fitness journeys. He believes in the power of education and strives to make complex fitness concepts accessible to everyone. His articles are thoroughly researched, drawing on the latest scientific studies and expert insights. When he's not writing or coaching, you can find Calvin in the gym, experimenting with new workout routines, or exploring the latest advancements in fitness technology. His dedication to the field of fitness and wellness is evident in his articles, which aim to inspire and inform readers on their path to a healthier, happier life.