Nootropics are a brand new type of cognitive enhancing drug, they are not regulated i the US and most are still pending FDA approval. Nootropics also pose no notable side effects (unless stated otherwise) as long as proper dosage instructions are followed.


Sunifiram is one of the newest nootropics on the market showing very promising initial results. It falls into the ampakine family of nootropic supplements because it is an AMPA agonist. Some reviews have suggested that it works similarly to Piracetam but it is over 1000 times more potent than Piracetam for the same dosage.

Sunifiram is highly effective at boosting memory function as well as attention span, learning, decision making and alertness. A lot of initial reviews and user experiences suggest that Sunifiram could become one of the most popular nootropic study aids for improving concentration.

Sunifiram works very similarly to other racetams by stimulating many of the same receptors just in different ways. The primary effect of taking Sunifiram is stimulation of AMPA receptors (hence which this drug is considered an AMPAkine).

In clinical trials, patients given the AMPA antagonist NBQX and then given Sunifiram saw increased AMPA receptor activity. AMPA receptors are responsible for how much glutamate is produced in the brain. Glutamate is perhaps the most important neurotransmitter in the brain, responsible for communicating excitatory transmissions, forming connections between synapses, and for regulating brain cell survival.

Glutamate is highly involved in brain metabolism as well as synaptic plasticity. Too little glutamate and your cognitive abilities will be greatly impaired, resulting in less attention span, poor ability to learn information and difficulty remembering. Sunifiram can help reverse this by raising levels of glutamate so your brain performance is increased. Especially when engaging in long periods of mental exertion, you will find that Sunifiram makes it easier to remember information and learn new concepts.

Sunifiram also effects levels of acetylcholine in the brain just like Piracetam, Pramiracetam, Aniracetam, Oxiracetam and other racetam nootropics. Studies have established that taking Sunifiram is Cholinergic meaning that it causes more of this neurotransmitter to be released.

Increased presence of Acetylcholine in the cerebral cortex leads to improved thinking, perception, alertness, learning, memory and focus. Acetycholine makes it easier for your left and right brain hemispheres to communicate as well which can cause you to recognize patterns and connections more effectively as well as improve basic social skills like talking in group settings.



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Note; dosage information is only for scientific reference purposes. SARMs Central, does not condone the human consumption or use of this substance outside of a controlled scientific environment (i.e. a lab).

Sunifiram is incredibly concentrated compared even to the strongest racetams like Pramiracetam. You will see positive effects from a dosage as small as 4 mg though many people typically take between 5-8 mg at a time. A Sunifiram dose of 10 mg is more likely to cause a stimulant effect similar to Adderall.

Taking a 10 mg Sunifiram dosing is not toxic and not likely to cause serious negative side effects, however you may experience increased body temperature and perspiration. You should start with a half dose of 3 mg for your first week or so of taking this ampakine nootropic and then only increase the dosage if you feel comfortable.

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Calvin Ramos

Calvin Ramos is a dedicated research and fitness enthusiast with a passion for helping individuals achieve their health and wellness goals. With years of experience in the fitness industry and a deep commitment to staying up-to-date with the latest research and developments in the field, Calvin brings a wealth of knowledge and expertise to his articles. As a fitness coach and nutrition specialist, Calvin has helped countless clients transform their lives through personalized training programs and evidence-based dietary recommendations. He holds a Bachelor's degree in Exercise Science and Nutrition from University and is certified in personal training and sports nutrition. Calvin's writing reflects his commitment to providing accurate and trustworthy information to empower readers on their fitness journeys. He believes in the power of education and strives to make complex fitness concepts accessible to everyone. His articles are thoroughly researched, drawing on the latest scientific studies and expert insights. When he's not writing or coaching, you can find Calvin in the gym, experimenting with new workout routines, or exploring the latest advancements in fitness technology. His dedication to the field of fitness and wellness is evident in his articles, which aim to inspire and inform readers on their path to a healthier, happier life.