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HGH Fragment Peptide 176-191 Peptide Guide: Mechanism, Benefits, Effects, Dosage, and More

Table of Contents

What is HGH Fragment 176-191

HGH Fragment 176-191 is a synthetic 16-amino acid peptide derived from the C-terminal region of human growth hormone (amino acids 176–191). It is studied for its fat-reducing effects without impacting growth or insulin activity. Preclinical studies show enhanced lipolysis in animals, and early in vitro evidence suggests it may boost the anti-cancer effect of breast cancer therapies when delivered via nanoparticles. [R]

Product Information

This peptide is supplied as freeze‑dried powder, reconstituted with bacteriostatic water and administered subcutaneously using micro‑dose syringes. Dosage is generally expressed in micrograms (µg) and may be split across the day due to its short half‑life. Store refrigerated after reconstitution.

HGH Fragment – Mechanism of Action

The mechanism of action of HGH Fragment 176-191 involves its ability to mimic certain effects of the full-length human growth hormone (GH) while avoiding others. Here’s a breakdown of its potential mechanisms:

HGH Fragment 176-191 structure

 

  • – Does not bind full-length GH receptors or induce growth, targeted to fat tissue.
  • – Stimulates lipolysis via β3-adrenergic receptors in adipose tissue, increasing fat breakdown and energy output.
  • – May enhance insulin sensitivity and blood glucose regulation.

HGH Fragment 176-191 Peptide – Benefits

HGH Fragment 176-191, a modified form of the growth hormone, is often associated with several potential benefits. Here are some commonly mentioned benefits:

Fat Loss: Promotes fat metabolism and adipose reduction in animal models without affecting appetite. {R}

Muscle Preservation: May help preserve lean mass during fat loss. {R}

Insulin Support: Animal studies suggests improved insulin sensitivity and glucose handling.

Cartilage Repair: Early animal data indicates regenerative effects in osteoarthritis.

Experimental Oncology: In vitro studies suggest enhanced drug delivery and tumor targeting when used in nanoparticle form.

Recommended Dosage of HGH Fragment 176-191

Common research dosages range from 200–500 µg/day administered subcutaneously. Due to its short half-life, dosing may be split (e.g., morning and evening). These are based on preclinical data and should be used under expert guidance.

Side Effects

While HGH 176-191 is often considered to have a more targeted action compared to the full-length growth hormone, it’s essential to recognize that it may have potential side effects. Here are some potential side effects:

  • Possible injection-site irritation or reaction.
  • Occasional nausea or headaches, and in rare cases, fatigue or joint pain.
  • High doses of related GH compounds have been associated with fluid retention or insulin resistance, though such effects are less documented with this fragment.

Is HGH Fragment Legal?

HGH  176‑191 is classified as a peptide for research use only. It is not approved for human therapeutic use and cannot be legally marketed as a drug or supplement in most jurisdictions.

Where to Buy HGH Fragment 176-191 Online?

While PureRawz offers HGH Fragment 176-191 in 2 mg injectable vials., BehemothLabz offers the supplement as a nasal spray of 50 mcg per bottle. This diversity allows customers to choose the format that aligns with their preferences and ease of use. Both the research chemicals suppliers provide reference material with every product they sell. Moreover, each of their products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.  

 

 

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