The circadian rhythm and metabolism are crucial physiological processes that play vital roles in maintaining overall health and well-being. The interplay between these two systems is intricate, and disruptions in their functioning can have significant implications for various aspects of health. SR-9011 is a synthetic compound that has garnered attention for its potential benefits, particularly in the fields of circadian rhythm regulation, metabolism, and physical performance.

SR-9011 Liquid
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Product Information

SR-9011 is a synthetic compound that belongs to the class of Rev-Erb agonists. Rev-Erb proteins play a crucial role in regulating the body’s circadian rhythm and metabolism. The compound SR-9011 specifically targets Rev-Erbα, one of the two isoforms of the Rev-Erb protein. It is primarily known for its potential effects on circadian rhythm regulation, metabolism, and physical performance.

SR-9011 is a synthetic compound with a chemical structure designed to interact with the Rev-Erbα protein, influencing circadian rhythm and metabolic processes.

Similarity with SR-9009:

Similar to SR-9009, SR-9011 acts as a Rev-Erb agonist. It binds to and activates Rev-Erbα, which, in turn, influences the expression of genes related to circadian rhythm and metabolism. For a detailed article on SR-9009 click here.

How Does it Work?

SR-9011 works by binding to Rev-Erbα and activating it. The nuclear receptors of Rev-Erbα, in turn, play a vital role in regulating the expression of genes involved in various physiological processes, including circadian rhythm, metabolism, and inflammation. {R}

Once SR-9011 binds to Rev-Erbα, it modulates the activity of this nuclear receptor. Rev-Erbα, in turn, acts as a transcription factor, influencing the expression of various genes. The modulation of gene expression by SR-9011 affects pathways related to circadian rhythm regulation and metabolism. {R}

The circadian rhythm is the internal clock that regulates various biological processes in a 24-hour cycle. Rev-Erbα is a key player in this regulation. By modulating the activity of Rev-Erbα, SR-9011 influences circadian behavior, potentially leading to improvements in sleep-wake cycles and overall physiological functions tied to the internal clock. {R}

Research suggests that SR-9011 can impact metabolism by influencing the expression of genes involved in glucose and lipid metabolism. This could have potential implications for conditions related to metabolic disorders, such as obesity and diabetes. {R}

The modulation of circadian rhythm and metabolism by SR-9011 has led to investigations into its potential therapeutic applications. Researchers are exploring its effects on conditions such as metabolic disorders, neurodegenerative diseases, and even certain types of cancer. {R}

SR-9011 Benefits

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Here are some potential benefits associated with SR-9011 based on existing studies:

1. Circadian Rhythm Regulation:

SR-9011 interacts with the Rev-Erbα protein, a key regulator of the circadian rhythm. By modulating the activity of Rev-Erbα, SR-9011 may contribute to the regulation of the body’s internal clock. This could lead to improved sleep-wake cycles and overall circadian rhythm health. {R}

2. Metabolic Effects/ Weight Loss:

Studies suggest that SR-9011 may influence the expression of genes involved in glucose and lipid metabolism. This could have potential implications for metabolic disorders, such as obesity and diabetes. By promoting a healthier metabolic profile, SR-9011 may contribute to better overall metabolic function. {R}

3. Enhanced Endurance and Physical Performance:

Some research indicates that SR-9011 may enhance endurance and physical performance. By influencing the circadian rhythm and metabolism, the compound may contribute to increased energy levels in the skeletal muscle and improved exercise capacity. This potential benefit could be of interest to athletes and individuals engaged in regular physical activities. {R}

In mice treated with SR9011, it was also demonstrated that the circadian pattern of expression of many metabolic genes in the liver, skeletal muscle, and adipose tissue was changed, leading to an increase in locomotor activity and energy consumption. {R}

4. Fatigue Reduction:

The increased endurance associated with SR-9011 may contribute to the reduction of fatigue. This could be particularly beneficial for individuals facing physical challenges or engaging in activities that demand sustained effort as compared to people with normal activity. {R}

5. Potential Cognitive Benefits:

As circadian rhythm regulation is closely tied to cognitive function, there is speculation that SR-9011 might have cognitive benefits. While more research is needed in this area, the compound’s influence on the internal clock could have implications for cognitive processes and alertness.

6. Potential Therapeutic Applications:

To find out whether SR 9011 could have an impact on the immune response and cell metabolism of the immune cells in the brain, a dose-response study on the cell cycle was recently carried out. According to the study’s findings, this research molecule may be used as a therapeutic target to treat neuro-inflammatory illnesses, including metabolic disorders, neurodegenerative diseases, and cancer. {R}

7. Potential Cancer Treatment:

A recent study has revealed that while cancer cells thrive on altered metabolic homeostasis, therefore, reactivating a circadian clock component could be a novel approach to deprive cancer cells of a metabolic state that fuels tumor growth. {R}

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SR-9011 Side Effects

Individuals considering the use of SR-9011 or similar compounds should be aware that there can be a few side effects with its numerous advantages as well. Some side effects that have been reported are:

Disruption of Circadian Rhythm:

Disrupting the natural circadian rhythm could potentially lead to adverse effects on sleep patterns, alertness, and overall well-being.

Effects on Metabolism:

Since SR-9011 has been associated with metabolic effects, there is a possibility of unintended consequences on metabolic processes. This could have implications for individuals with existing metabolic conditions.

Is It Legal?

SR9011 is only legal to buy or sell for laboratory research use. While the FDA has not given it a legal status as a supplement yet, however, things do look positive for SR-9011 with further research.


To attain its optimum effects, a starting dose of 10 mg per day is recommended. Remember that the lower your dosage, the less likely you are to encounter side effects, 

If you’re a beginner, we recommend you purchase just one vial of SR9011 from Pure Rawz, and take half a dropper per day for 60 days for your first cycle—this will get you some great results.

Buy SR-9011 Stack – Pure Rawz

What is the Half-Life of SR-9011?

SR9011 has a relatively short half-life of 4 hours.

Where can I buy SR-9011 Online?

The quality of SR-9011 supplements can vary between brands. Choose products from reputable manufacturers, and consider consulting with a healthcare professional for guidance on selecting a high-quality supplement.

We recommend Pure Rawz, Behemoth Labz, and RCD.Bio is the best place to buy SR-9011. While Behemoth Labz provides SR-9011 both in capsule and liquid forms, RCD.Bio has the compound available in liquid form only. Pure Rawz provides SR-9011 in stack form to their online customers. To be the best suppliers of research chemicals, both online stores provide reference materials with every product they sell.

About Author

Calvin Ramos

Calvin Ramos is a dedicated research and fitness enthusiast with a passion for helping individuals achieve their health and wellness goals. With years of experience in the fitness industry and a deep commitment to staying up-to-date with the latest research and developments in the field, Calvin brings a wealth of knowledge and expertise to his articles. As a fitness coach and nutrition specialist, Calvin has helped countless clients transform their lives through personalized training programs and evidence-based dietary recommendations. He holds a Bachelor's degree in Exercise Science and Nutrition from University and is certified in personal training and sports nutrition. Calvin's writing reflects his commitment to providing accurate and trustworthy information to empower readers on their fitness journeys. He believes in the power of education and strives to make complex fitness concepts accessible to everyone. His articles are thoroughly researched, drawing on the latest scientific studies and expert insights. When he's not writing or coaching, you can find Calvin in the gym, experimenting with new workout routines, or exploring the latest advancements in fitness technology. His dedication to the field of fitness and wellness is evident in his articles, which aim to inspire and inform readers on their path to a healthier, happier life.