Sarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
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View ProgramsSarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
PROHORMONES
- AAS
About
View ProgramsSarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
AAS
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About
View ProgramsSarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
PEPTIDES
- NOOTROPICS
About
View ProgramsSarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
NOOTROPIC
Latest Blog
- OTHER COMPOUNDS
About
View ProgramsSarmscentral is a leading online retailer specializing in high-quality Selective Androgen Receptor Modulators (SARMs). Our mission is to provide athletes, bodybuilders, and fitness enthusiasts with the best possible products to help them achieve their goals.
OTHER COMPOUNDS
SR-9011
Overview
SR9011 is a REV-ERB-α/β agonist.
REV-ERB nuclear receptors have a critical role in feedback regulation of the circadian oscillator. Both Bmal1 and Clock are direct REV-ERB target genes and loss of REV-ERB-α alters circadian behaviour.
In vitro: SR9011 dose-dependently increased the REV-ERB-dependent repressor activity assessed in HEK293 cells. In addition, SR9011 potently and efficaciously suppressed transcription in a cotransfection assay using full-length REV-ERB-a along with a luciferase reporter driven by the Bmal1 promoter.
SR9011 also suppressed the expression of BMAL1 messenger RNA in HepG2 cells in a REV-ERB-a/b-dependent manner. Moreover, SR9011 inhibited the activity of the SCNclock, with reversible inhibition of circadian oscillations.
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Buy Now Dosage
Note; dosage information is only for scientific reference purposes. SARMs Central, does not condone the human consumption or use of this substance outside of a controlled scientific environment (i.e. a lab).
As a general guideline we would suggest 'testing' a new SARM at about 10-15 mg per day and see how your body reacts. If you don't experience any adverse effects or results you can steadily start increasing the dosage by 10mg per day. When in doubt remember we're always here to offer advice, feel free to contact us if you have any questions.
