If you want to build more muscle and look more ripped, you’ve probably heard of prohormones. Fun fact: it was once considered the secret weapon among elite bodybuilders. But now, in 2025, they’re back and better. With new and improved formulas, prohormones can help you out. This guide will show you the best ones to use for building muscle. Whether you want to push your workouts further or just learn what prohormones do, this is the guide for you.
How Prohormones Work
Prohormones are special compounds. This can turn into muscle-building hormones after your body processes them. Unlike some steroids like Dianabol or Durabolin, prohormones are still legal in many places. You can find them as pills, liquids, or creams that you put on your skin. People use them to boost testosterone, build muscle, and get stronger. They’re mostly used by bodybuilders and athletes.
Benefits of Using Prohormones
- ➢ Increased muscle mass
- ➢ Enhanced strength and power
- ➢ Improved muscle definition
- ➢ Boost in testosterone levels
- ➢ Faster recovery times
Top Prohormones for Muscle Growth in 2025
1-Andro (DHEA)
1-Andro, also known as 1-DHEA, is a prohormone that converts in the body to 1-Testosterone. It’s considered a muscle-building hormone that is widely used for lean muscle growth, strength gains, and dry mass.
Forms Available
- ➢ 1-Andro Liquid
- ➢ 1-Andro Capsules
- ➢ 1-Andro Transdermal
4-Andro (4 DHEA)
4-Andro is considered a strong prohormone supplement that also converts into testosterone in the body. However, unlike 1-Andro, this converts into actual testosterone. This leads to more water retention and stronger androgenic effects. That’s why it’s ideal for those who chase ultimate mass.
Forms Available
- ➢ 4-Andro Capsules
- ➢ 4-Andro Liquid
- ➢ 4-Andro Transdermal
Epiandrosterone (Epi-Andro)
Epiandrosterone, which is often shortened to Epi-Andro, is a naturally occurring DHEA derivative that converts into dihydrotestosterone (DHT). That’s why it can aid in fat loss and cutting cycles. Some of its many key effects are how it can improve muscle density, vascularity, and dry gains.
19-NorAndro (19-NorDHEA)
19-NorAndro is a prohormone that converts into Nandrolone (Deca-Durabolin). It’s a powerful anabolic compound known for joint support and solid mass gains. Due to its Deca-like properties, this enhances the users’ strength, endurance, and muscle size. It’s commonly recommended for bulking, mass cycles, and those with joint pain or overuse injuries.
7-Keto DHEA
7-Keto DHEA is a non-androgenic metabolite of DHEA. That’s why, unlike most prohormones, 7-Keto DHEA doesn’t convert into testosterone or estrogen. Instead, it’s mostly used to support fat loss and metabolism. Instead, it’s used to support fat loss and boost metabolism. Without impact on the user’s hormone levels
Superdrol
Superdrol is an extremely potent methylated anabolic prohormone. It’s known for delivering explosive strength and massive muscle gains in a short period. Because of this, it can mimic the effects of anabolic steroids but in oral supplement form. However, Superdrol is considered toxic to the liver, and it could suppress natural testosterone.
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Choosing The Right Prohormones for Muscle Growth
To choose the right prohormone is to pick the right compound that matches your goal. The “right” prohormone also depends on your preference and background. The right prohormone is important to learn first, as it can help you get better results with fewer side effects.
Here are sample prohormones based on the results you wanted to achieve:
- ➢ Prohormones for lean and dry gains: 1 Andro
- ➢ Prohormones for bulking and strength boost: 4- Andro
- ➢ Prohormones for massive gains: Superdrol
Prohormone Stack for Best Results
- ➢ Goal: Build quality lean muscle with strength gains with minimal water retention.
Compounds: 1-Andro capsules/liquid (300-400 mg/day), Epiandrosterone (200-300 mg/day), Plex (follow prescribed dosage)
Cycle length: 6 weeks
PCT: Clomid or Nolvadex for 4 weeks post-cycle - ➢ Goal: Maximize size and strength with noticeable weight gain
Compounds: 4-Andro capsules/liquid (400-600 mg/day), Superdrol-oral (10-20 mg/day), Andriol (follow prescribed dosage)
Cycle length: 4 weeks (Superdrol in maximum: 4 weeks)
PCT: Strong PCT essential (Clomid/Nolvadex and natural boosters) - ➢ Goal: Gain hard, dry muscle with improved vascularity and strength.
Compound: 1-Andro Capsules/Transdermal (300-400 mg/day), Trenabol (20-30 mg/day), Epiandrosterone (200 mg)
Cycle length: 6 weeks
PCT: Clomid or Nolvadex for 4 weeks post-cycle - ➢ (Beginner prohormone stack) Goal: Introduce prohormones mildly with moderate gains and minimal side effects.
Compound: 4-Andro Capsules (200 mg/day), Epiandrosterone (150-200 mg/day)
Cycle length: 4 weeks
PCT: Mild PCT (natural boosters like DAA, ZMA)
How to Use Prohormones Safely
- ➢ Choose the right prohormone for your goal
- ➢ Do careful research on the right prohormone stack for your goal
- ➢ Plan your cycle carefully
- ➢ Take cycle support supplements
- ➢ Always follow with Post Cycle Therapy (PCT)
- ➢ Don’t run prohormones back-to-back (always allow at least 8 weeks off after PCT)
Potential Side Effects
Always remember that with great gains come potential health risks. Here are the common prohormone products’ side effects to be aware of:
- ➢ Testosterone suppression
- ➢ Acne, oily skin
- ➢ Mood swings or aggression
- ➢ Hair thinning
- ➢ Elevated liver enzymes
- ➢ Decreased libido if post-cycle therapy is ignored
After, you must have quality cycle support during your run and always follow up with strong post-cycle therapy.
Conclusion
The best prohormones for muscle growth in 2025 really come down to your preference. Whether you’re building a prohormone cycle or simply experimenting with 1-Andro, the key is preparation. That’s why it’s best to consult a legal provider to carefully study the suited prohormone for you.
Frequently Asked Questions
Are prohormones legal in 2025?
Yes, but only some prohormones are legal. Still, others are banned or controlled; that’s why it’s best to research first, depending on the laws in your area. In the U.S., the Designer Anabolic Steroid Control Act of 2014 banned many methylated and stronger anabolic prohormones like Superdrol, Halodrol, and Trenabol. However, non-methylated DHEA-based prohormones like 1-Andro, 4-Andro, and most on the list above are still legally sold as prohormones for 2025.
Can I gain muscle and manage muscle building without using prohormones?
Absolutely. While prohormones can accelerate muscle gains, they’re not the only choice. However, to build serious size and strength naturally may require more effort.
How long does it take to see results?
While it’s important to note that the results vary depending on the type of prohormone used, including how it’s maintained/administered, most users report noticeable changes as early as one week. To be exact, for enhanced pumps, it takes between 1-2 weeks. 3-4 weeks for visible muscle fullness and reduced fat. 4-6 weeks for its peak performance, wherein the user’s body composition changes.
Do I always need PCT?
Yes, always. Post Cycle Therapy (PCT) is a must after any prohormone cycle. Even mild prohormones like 1-Andro or 4-Andro can suppress your body’s natural testosterone production. Without PCT, you risk hormonal imbalances that may cause mood swings or depression and strength loss. Even during cycles, support supplements are recommended alongside PCT afterward.
