Introduction

Dosage and Cycles chart for HRT

Confused about what your HRT dosage and cycle plan should look like? You are not alone. Many people resort to HRT solutions without fully understanding the dosage and cycles of it. Hormone Replacement Therapy (HRT) is the medical answer to the problem of hormonal imbalance. So, naturally, HRT’s effectiveness and safety will depend only on accurate dosing and proper cycle management. This article provides a guide for you so that you can have a proper chart for your dosage and HRT cycles.

Introduction

Dosage and Cycles chart for HRT​

Confused about what your HRT dosage and cycle plan should look like? You are not alone. Many people resort to HRT solutions without fully understanding the dosage and cycles of it. Hormone Replacement Therapy (HRT) is the medical answer to the problem of hormonal imbalance. So, naturally, HRT’s effectiveness and safety will depend only on accurate dosing and proper cycle management. This article provides a guide for you so that you can have a proper chart for your dosage and HRT cycles.

SARMs function

Understanding HRT

Hormones are the elements that control your body’s functions. They regulate metabolism, mood, strength, energy levels, and overall well-being. As we age, hormone production naturally declines. This leads to many physical and emotional symptoms. HRT aims to bring those hormone levels up to an optimum level.  So basically, it’s not just restoration of hormones but also ensuring that they perform in harmony for better health and longevity.

There are two primary categories of HRT:

  1. Men’s HRT: This treatment’s goal is to restore testosterone. With it, HRT for men also boosts DHEA, growth hormone, and other androgens.
  2. Women’s HRT: This treatment’s goal is to restore estrogen and progesterone. However, many women have an imbalance of testosterone or thyroid hormones. Women’s HRT targets that area as well.

Factors

Factors Influencing SARMs Dosage

First-time SARM users tend to have a much lower tolerance and are advised to stick to a lower dosage. It is important to assess how the body responds to these powerful compounds. More experienced users are familiar with the potential effects and unwanted side effects. They are more familiar with how the body reacts and will be able to better monitor dosage and cycle length.

Because each SARM has different effects and properties, it’s key to find the right compound that suits your fitness goals. Ostarine is known for helping with cutting phases and muscle preservation, while a powerhouse like Ligandrol is known for bulking.

To make sure you achieve your fitness goals, make sure you are on the correct SARM cycle.

Gender is an interesting topic for debate when it comes to SARMs. Men tend to find SARMs appealing as it is a safer alternative to conventional anabolic steroids.

However, they are also quite popular amongst women seeking a muscle-building agent with less effects on hormone balance. Unlike most anabolic steroids, they do not cause a deeper voice and male-pattern hair growth.

Gender does in fact play a vital role in determining the dosage, risks, and effects associated with SARMs. Women should approach SARMs more cautiously as opposed to men. This typically means administering lower dosages to reduce and minimize the risk of androgenic side effects. Men can tolerate higher dosages with more pronounced effects.

Body weight can significantly influence the effectiveness of a SARM cycle. As with most compounds, body weight impacts how a SARM is metabolized, and the dosage needed for effective results. Individuals with a higher body weight may need an increased dosage to achieve results similar to those of someone with a lower body weight.

SARM potency directly affects the dosage and cycle length. More potent SARMs generally require smaller doses to achieve effective results as opposed to less potent SARMs. This is also applicable to the form of SARMs such as tablets or liquids. The oral bioavailability of a liquid tends to be much higher than that of a capsule or tablet. Liquids have faster absorption and are more efficiently absorbed into the bloodstream.

Why Does the Right Cycle Matter?

When it comes to HRT, the dosage cycle is everything. It’s not just about taking hormones, but the idea is to balance them. We do not want hormonal decline, but we also do not need excess. Here are a few pointers on why a proper chart is important. 
  • Hormones Work in Balance. They cannot benefit in isolation
  • The right dosage cycle prevents side effects
  • It optimizes results and benefits such as:
    1. Increased energy and stamina
    2. Better muscle tone and metabolism
    3. Enhanced libido and sexual function
    4. Improved mental clarity and sleep quality
    5. Youthful skin and vitality
  • It reduces the risk of suppression or shutdown
  • Enables accurate monitoring and adjustment
  • Protects organ health
  • It gives psychological and emotional stability

Detailed Hrt Dosage Chart

Men’s HRT Dosage Chart

HormoneTypical DosageFrequencyFormCycle DurationRemarks
Testosterone Cypionate/Enanthate100–200 mgWeekly (1–2 injections)InjectableContinuousStart at 100 mg/week. Adjust based on blood levels.
HCG (Human Chorionic Gonadotropin)250–500 IU2–3x weeklyInjectableAlongside TRTHelps preserve fertility and natural testosterone production.
Anastrozole (Aromatase Inhibitor)0.25–0.5 mg2x weeklyOralAs neededControls estrogen conversion; monitor E2 levels.
DHEA (Dehydroepiandrosterone)25–50 mgDailyOralContinuousSupports testosterone synthesis and energy levels.
GH Peptides such as Ipamorelin + CJC-1295)100–200 mcg each1–2x dailyInjectable (subQ)3–6 monthsPromotes growth hormone release and lean muscle growth.
Pregnenolone25–50 mgDailyOralContinuousBoosts mood and mental function.
 

Women’s HRT Dosage Chart

HormoneTypical DosageFrequencyFormCycle DurationRemarks
Estradiol (E2)0.25–1 mgDailyOral / Transdermal / InjectableContinuous or cyclicalUsed to relieve menopause symptoms and balance estrogen.
Progesterone (Micronized)100–200 mgNightlyOral / Transdermal12–14 days/month (cyclic) or dailyProtects uterine lining and supports mood/sleep.
Testosterone (Low Dose)2.5–10 mgDailyTopical / InjectableContinuousHelps libido, energy, and muscle tone.
DHEA10–25 mgDailyOralContinuousEnhances mood and balances estrogen/testosterone.
Thyroid Hormones (T3/T4)VariableDailyOralContinuousBalances metabolism and energy levels.
Melatonin / Peptides (GHRP-2, CJC-1295)100–200 mcg1–2x dailyInjectable (subQ)2–4 monthsSupports sleep, recovery, and growth hormone production.

Note

Dosage Range (mg/day)

The range represents a minimum and maximum dose; users should start with the lower end and increase if tolerated well. Dosage can be adjusted according to SARM form such as liquid sarms, capsules, powder etc.

Cycle Length

Suggested duration in weeks for a cycle. Prolonging cycles beyond these recommendations can increase risk and sticking to guidelines, concentrations, and strengths is always the best practice.

Side Effects

 Common side effects associated with each SARM; vary by individual tolerance.

HRT Cycle Timing and Adjustments

Proper HRT management requires regular testing. It also needs adjustments along the way. At the start, bloodwork should be conducted every 8–12 weeks. You should check the following in the tests:
  • Total and Free Testosterone
  • Estradiol (E2)
  • LH & FSH
  • SHBG
  • DHEA-S
  • Thyroid profile (T3, T4, TSH)
  • Lipid panel and liver enzymes

Seeing the above symptom feedback, you should make adjustments.

 

Common HRT Cycles:

Men’s TRT Sample Cycle (12 Weeks):

  • Testosterone Enanthate: 150 mg weekly
  • HCG: 500 IU twice weekly
  • Anastrozole: 0.25 mg twice weekly (as needed)
  • Peptides: CJC-1295 100 mcg + Ipamorelin 100 mcg before bed

Women’s HRT Sample Cycle (8 Weeks):

  • Estradiol (transdermal): 0.5 mg/day
  • Progesterone: 100 mg at bedtime (days 15–28)
  • DHEA: 10 mg/day
  • Low-dose testosterone cream: 2.5 mg/day

A standard HRT cycle consists of three phases:

  1. Initiation Phase (Weeks 1–8): Low starting doses to stabilize hormone levels and assess response.
  2. Optimization Phase (Weeks 9–24): Gradual adjustments to reach optimal hormone levels and maximize benefits.

Maintenance Phase (Ongoing): Steady-state dosing with regular monitoring every 3–6 months.

Detailed SARMs Dosage Chart

HRT Peptide Support (Optional Add-ons)

PeptideTypical DosagePurpose
CJC-1295 + Ipamorelin100–200 mcg each 1–2x/day

Boosts GH production

Improves sleep

Recovery

Body composition

BPC-157250–500 mcg/day

Tissue and gut repair

Anti-inflammatory

TB-500 (Thymosin Beta-4)2–5 mg/week

Accelerates recovery

Healing

Epithalon10 mg/day for 10 days (quarterly)

Promotes longevity

Regulates melatonin 

Cell regeneration

Kisspeptin-10100 mcg 2–3x/week

Boosts natural gonadotropin release for fertility and testosterone

Safety and Monitoring

HRT cycles should always be personalized. Expert medical supervision is a must, also. Overdosing or poor management can lead to side effects such as:

  • Estrogen dominance or imbalance
  • Gynecomastia (men)
  • Acne or oily skin
  • Water retention
  • Mood swings or irritability
  • Altered lipid levels

To Mitigate risks

  • One should do regular blood testing.
  • Should stay hydrated and keep a clean diet. It should be rich in omega-3s and micronutrients.
  • Combine HRT with exercise too. This will optimize insulin sensitivity and improve heart health.

Conclusion

An effective HRT program is not a single package that can be sold to all. It is not a one-size-fits-all formula. A good effective program is a perfect balance of hormones needed for the individual. It’s a carefully balanced protocol. The balance depends on the user’s biochemistry, age, and health goals. With the correct dosages and cycles, consistent monitoring, and the right blend of peptides or supplements, HRT can restore vitality, muscle strength, sexual health, and cognitive clarity. HRT can make you live stronger and longer.

When starting or adjusting an HRT cycle, always go to the experts. Sarmcentral recommends PrometheuzHRT as one of the best places to go for HRT. They give you personalized hormone replacement therapy (HRT) to restore balance that improves overall wellbeing.

Safety

HRT Cycle Timing and Adjustments

HRT is not like steroids. So you do not have to cycle off completely. Most individuals stay on continuous HRT. They do minor adjustments every 3–6 months based on labs and symptoms and they are good to go. 

Yes. Peptides like CJC-1295, Ipamorelin, and BPC-157 work great with HRT. The results can boost recovery, growth hormone production, and tissue health.

Most users report noticeable improvements within 4–8 weeks. However, full benefits appear after 3–6 months of consistent use.

Only if estradiol levels rise excessively, overusing blockers is bad for joint pain, fatigue, and low libido

Yes, they can, but in very low doses. It can boost mood, libido, and energy when balanced with estrogen and progesterone.

Yes, HRT is safe as long as it is being monitored by a qualified provider. HRT must also come with clean nutrition, fitness, and periodic lab checks.