SARMs have gained popularity in the bodybuilding community. While SARMs are already known for their proven beneficial effects on muscle growth, improved lean body mass, increased bone density, and potential performance enhancement, this article will specifically cover a brief introduction to SARMS and enlighten our readers on what SARMs can add to these already known health benefits.
AR or Androgen Receptors are known for muscle growth and development in the human body. SARMs specifically target the AR receptor tissue and trigger growth in muscle tissue by providing increased protein synthesis. SARMs promote muscle growth through androgen receptor targeting, but may still carry significant risks and side effects.
What are SARMs?
Selective Androgen Receptor Modulators, commonly known as SARMs, are a class of therapeutic compounds that have similar properties to anabolic steroids but with reduced androgenic (related to male sex hormones) properties.
They are designed to selectively target androgen receptors in the body, specifically those in muscle and bone tissue while minimizing the impact on other organs and tissues. This selectivity is believed to reduce the side effects commonly associated with traditional anabolic steroids.
Their tissue-selective activity gives SARMs the ability to stimulate muscle and bone growth while aiming to reduce side effects compared to steroids.
Animal studies suggest SARMs may exert anabolic effects comparable to a fraction of testosterone’s potency while showing reduced androgenic activity. {R}
Here are some key points to introduce and educate you on SARMs:
Mechanism of Action:
SARMs work by binding to androgen receptors in a tissue-selective manner. This means they aim to stimulate the androgen receptors in muscles and bones, promoting muscle growth and bone density, while minimizing activation in other tissues. While other compounds in the market are generic in their targeting of tissues and body receptors, Selective Androgen Receptor Modulators are very selective in their targeting of AR. Thus a selective androgen receptor modulator doesn’t affect the other remaining nuclear receptors including steroid receptors, resulting in minimizing unwanted side effects.
Uses and Applications of SARMs:
Medical and Research Applications:
Originally developed for medical purposes, Selective Androgen Receptor Modulators have been explored for treating conditions such as muscle wasting, osteoporosis, and hypogonadism. Their potential applications extend to the treatment of various diseases and conditions where the stimulation of muscle and bone growth is beneficial.
Muscle Building and Performance Enhancement:
Due to their ability to promote muscle growth and improve physical performance, Selective Androgen Receptor Modulators have gained popularity in the fitness and bodybuilding communities. Athletes and bodybuilders use them as alternatives to traditional steroids to achieve similar effects with potentially fewer side effects.
Popularity in the Bodybuilding industry
The compound is a Selective Androgen Receptor Modulator (SARM) which operates by binding androgen receptor ligands. Simply put, this means that by using the right dosage, androgen receptors in selective tissues tend to show androgenic signaling.
Originally developed to treat muscle wasting, osteoporosis, and hypogonadism with its selective AR targeting nature. Selective Androgen Receptor Modulators have proved to improve bone strength and exaggerate muscle growth by enhancing the body’s natural skeletal muscle hypertrophy.
Performance and Endurance Levels
Selective Androgen Receptor Modulators (SARMs) are a class of drugs that have been developed for various medical purposes, including the treatment of conditions like muscle wasting and osteoporosis.
As mentioned above, they work by selectively targeting androgen receptors in the body, which can have anabolic (muscle-building) effects similar to traditional anabolic steroids, but with potentially fewer side effects on other tissues.
Some athletes and bodybuilders have turned to SARMs. However, it’s important to note that the use of Selective Androgen Receptor Modulators for performance enhancement is often considered unethical and is banned by many sports organizations and anti-doping agencies.
Benefits of SARMs
Muscle Growth
They have shown promise in the promotion of muscle growth in various clinical trials. This could theoretically lead to increased strength and improved athletic performance. {R}
Body Fat Loss
Some Selective Androgen Receptor Modulators have been studied for their potential to help with body fat loss. This is in addition to providing increased muscle mass and bone density enhancement. With the right dosage, protein increases muscle mass and decreases fat mass in research conducted on castrated mice. {R}
Recovery
While Selective Androgen Receptor Modulators primarily target muscle tissue, users have reported improved endurance and recovery, possibly due to increased muscle mass and reduced muscle fatigue. {R}
Some users report improved workout endurance and faster recovery, though evidence is anecdotal. {R}
Some Notable SARMs:
Examples include but are not limited to.
- Ostarine (MK-2866)
- Ligandrol (LGD-4033)
- Andarine (S-4)
- Rad-140 (Testolone).
Side Effects and Risks:
Although SARMs were developed to reduce side effects compared to steroids, studies show they can still cause serious health risks. Typically, these side effects are the result of over-ambition resulting in over-dosage of the product, not adhering to comprehensive guidelines, and not consulting healthcare providers before use. Studies and reports show health problems may include {R}:
- Increased risk of heart attack or stroke
- Sleep disturbances
- Liver injury and acute liver failure
- Pregnancy complications
Research and Development:
Research into Selective Androgen Receptor Modulators is actively ongoing, with scientists exploring new compounds and the relevance of their potential applications daily. Continued investigation is necessary to better understand their long-term effects, safety, and potential therapeutic uses.
It’s crucial to note that the information and understanding of Selective Androgen Receptor Modulators may evolve as more research is conducted. Before considering the use of SARMs, individuals should consult with healthcare professionals to understand potential risks and benefits based on their specific health conditions and goals.
The research compound is known for its potential to increase muscle mass and aid bone density enhancement. However, PCT (post-cycle therapy) may also be needed with the use of most Selective Androgen Receptor Modulators.
Dosage
As obvious, gender, weight, body type, and medical history are major factors based on the dosage of SARM that should be set by a professional healthcare provider. Generally, based on average users, it is recommended that SARMs (in general) may be taken at a dose of 10-20 mg for 30 to 60 days.
Are SARMs Legal?
SARMs are not FDA-approved and are considered unsafe for human consumption. They are also banned by WADA and most sports organizations.
Where to Buy Sarms?
To source the best SARM suppliers, we recommend sites that provide reference materials with every product they sell. Always be on the lookout for sites that provide SARMs with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.
We recommend checking the manufacturer’s instructions on the packaging before use.
