Do you think your heart health is degrading by the day? Do you worry about your kidneys functioning properly? Are you seeking to supercharge your brain and make yourself younger once again? Don’t worry. The peptide that we have for you today is called Elamipretide. Also known as SS-31, it is a small peptide best for the treatment of all kinds of mitochondrial diseases.

Mitochondria is the powerhouse of the cell that plays a very important role in energy production. If it dysfunctions, a range of chronic conditions can occur. These diseases can include heart disease, neurodegenerative disorders, and muscle weakness. SS-31 is designed to target and stabilize mitochondria. This stable behaviour improves heart function and eliminates disease symptoms that occur with mitochondrial dysfunction.

Product Information

  • Chemical Formula: C28H38N6O5
  • Molecular Weight: 558.64 g/mol
  • Sequence: D-Arg-Dmt-Lys-Phe-NH2
  • CAS Number: 736992-21-5
  • Storage: Store at -20°C, protected from light
  • Form: Typically available as a lyophilized powder for reconstitution at Purerawz.co and RCD.Bio

Elamipretide, as a product, is a tetrapeptide. This means that it is composed of four amino acids. These are D-Arginine, DimethylTryptophan, Phenylalanine, and Lysine (D-Arg-Dmt-Lys-Phe-NH2). What makes SS-31 unique is its ability to selectively target the inner mitochondrial membrane. Here it interacts with cardiolipin. It is a lipid that is needed for maintaining mitochondrial proper functioning. This interaction also preserves mitochondrial structure, reduces oxidative stress, and improves cellular energy production. Elamipretide is most commonly taken via subcutaneous injection. 

Mechanism of Action

The way SS-31 functions is by going after and guarding the mitochondria. These are the areas of our cells that make energy. It attaches itself particularly to cardiolipin. This is a unique molecule found in the mitochondria’s inner membrane. By doing this, SS-31 contributes to the stability and proper operation of the mitochondria. It resultantly lowers reactive oxygen species (ROS). The ROS are dangerous chemicals that have the potential to injure cells. The cell’s capacity to produce energy is enhanced by this protection against the ROS. It is important for high-energy organs like the heart and muscles. Furthermore, SS-31 aids in preventing cell death which occurs through mitochondrial damage. {R}

The mechanism involves the following 4 important steps:

  1. Targeting Cardiolipin
  2. Reduction of Oxidative Stress 
  3. Improvement in Mitochondrial Bioenergetics
  4. Anti-apoptotic Effects

Benefits of SS-31 (Elamipretide)

1.Transforms Cardiovascular Health Enhancing Strength and Resilience: 

SS-31 very successfully treats conditions like heart failure and ischemia-reperfusion injury. It even treats diabetic cardiomyopathy. By improving mitochondrial function, SS-31 improves cardiac muscle contractility, reducing the risk of arrhythmias. It protects against myocardial injuries as well. {R}

2. Supercharges Neuroprotection and Shields the Brain with Cutting-Edge Protection: 

Mitochondrial dysfunction is a hallmark of many neurodegenerative diseases. These include Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS). SS-31’s ability to reduce oxidative stress slows the progression of these diseases and improves brain function. {R} 

3. Maximizes Muscle Power and Elevates Physical Performance and Stamina:

Muscle weakness and fatigue are common symptoms of mitochondrial disorders. SS-31 improves muscle strength and endurance. It treats muscle diseases or age-related muscle decline. {R}

4. Revitalizes Kidney Function Ensuring Optimal Filtration and Vitality: 

Acute kidney injury (AKI) and chronic kidney disease (CKD) are all linked with mitochondrial dysfunction as well. SS-31 has renal protective effects slowing the progression of CKD. {R}

5. Unleashes Anti-Aging Power and Rejuvenates the Body and Mind: 

Mitochondrial dysfunction is a key contributor to the ageing process. By preserving mitochondrial function, SS-31 has anti-aging effects. This improves overall healthspan and reduces the incidence of age-related diseases. {R}

Usage Tips

  1. Consistency is key
  2. Start with a low dosage
  3. Typically, around 0.1 mg/kg to as high as 1.0 mg/kg is recommended.
  4. It’s best taken in the morning as its effects last longer.
  5. Stay hydrated when taking SS31.

User Reviews

Image source : Reddit 

Side Effects of SS-31

SS-31 has a very safe profile without any potential for side effects. It is mostly well-tolerated. However, some of the mild side effects that may occur for user’s info are:  

  • Injection Site Reactions
  • Gastrointestinal Symptoms
  • Fatigue
  • Headache
  • Allergic Reactions

Dosage

The ideal dosage of SS-31 can change based on a number of variables. These include the patient’s height, weight, and ailment. It can range from 0.1 mg/kg to 1.0 mg/kg in its lowest and highest values. You can take 2 mg/kg for the therapy of tumours from day 7 to day 13, 5 mg/mL from day 14 to day 20, and 10 mg/mL from day 21 to day 27. 

FAQs

1. What ailments might SS-31 be able to treat? 

Many disorders are linked to mitochondrial malfunction. These include heart failure, neurological diseases, muscle weakness and  renal damage. The peptide even treats age-related decline.

2. How is the SS-31 given out? 

The most popular way to use SS-31 is by subcutaneous injection. Other delivery routes such as intravenous are also being investigated.

3. Is it possible to treat ageing using SS-31? 

Yes, SS-31 is a very effective anti-ageing medication.

4. How is SS-31 unique from other treatments involving mitochondria? 

SS-31 affects mitochondrial activity and lowers oxidative stress. This makes it very unique and effective against various diseases without the side effects that other treatments possess.

Where to Buy SS31 (Elamipretide) Online?

The best online stores to buy synthetic peptides including SS31 as per our recommendation are Purerawz and RCD.Bio. Both stores offer the peptide in 99% purest form. RCD.Bio and Purerawz offer the peptide in injectable form.

SS31 – Buy from Purerawz

RCD.Bio has the product available in 10mg dosage injectable form. This diversity allows customers to choose the format that aligns with their preferences and ease of use.

Both research chemicals suppliers provide reference material with every product they sell. Moreover, each of their products comes with an independent, third-party-issued Certificate of Analysis for identification, purity, and concentration.

Conclusion

SS-31 (Elamipretide) is a great peptide effective for all kinds of mitochondrial dysfunction diseases. The peptide has proven itself very effective in improving heart health. It improves kidneys and safeguards the body against numerous cancerous and tumour diseases. SS31 supercharges the brain and induces neuroprotection in the body. It reduces muscle wasting and strengthens muscles. This resultantly eliminates fatigue and stress. To top it all, the peptide turns back the age clock and makes you younger. This is a super advantage for SS31 lovers as it makes the peptide more fascinating. With the right dosage and tips followed by Purerawz and RCD.Bio, SS31 becomes a best buy for people seeking supreme health.

About Author

Calvin Ramos

Calvin Ramos is a dedicated research and fitness enthusiast with a passion for helping individuals achieve their health and wellness goals. With years of experience in the fitness industry and a deep commitment to staying up-to-date with the latest research and developments in the field, Calvin brings a wealth of knowledge and expertise to his articles. As a fitness coach and nutrition specialist, Calvin has helped countless clients transform their lives through personalized training programs and evidence-based dietary recommendations. He holds a Bachelor's degree in Exercise Science and Nutrition from University and is certified in personal training and sports nutrition. Calvin's writing reflects his commitment to providing accurate and trustworthy information to empower readers on their fitness journeys. He believes in the power of education and strives to make complex fitness concepts accessible to everyone. His articles are thoroughly researched, drawing on the latest scientific studies and expert insights. When he's not writing or coaching, you can find Calvin in the gym, experimenting with new workout routines, or exploring the latest advancements in fitness technology. His dedication to the field of fitness and wellness is evident in his articles, which aim to inspire and inform readers on their path to a healthier, happier life.

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